Clinical Management of Squamous Cell Carcinoma of the Conjunctiva

• Published in: The American journal of case reports Vol. 21; p. e919751
• Main Authors: Röck, Tobias, Bartz-Schmidt, Karl Ulrich, Bramkamp, Matthias, Milla, Jakob, Bösmüller, Hans-Christian, Röck, Daniel
• Format: Journal Article
• Language: English
• Published: United States International Scientific Literature, Inc 01-02-2020
• ISSN: 1941-5923; 1941-5923
• DOI: 10.12659/AJCR.919751

BACKGROUND Conjunctival squamous cell carcinoma is the most common non-pigmented malignancy of the ocular surface. This report illustrates the clinical management of squamous cell carcinoma of the conjunctiva. CASE REPORT A 33-year-old female was referred to our eye hospital with a tumorous lesion on the nasal bulbar conjunctiva of the right eye. A topical therapy with antibiotic and corticosteroid eye drops did not change the lesion. The conjunctival tumor was widely resected. The histopathological diagnosis suggested a squamous cell carcinoma. After resection, a treatment with topical mitomycin C (MMC) 0.02% eye drops were started 4 times daily for 14 days. Two cycles of treatment were done with a 2-week interval during which only artificial tears eye drops were administered. At the 12-month follow-up, there was no sign of recurrence. CONCLUSIONS This case illustrates the effective and successful clinical management of squamous cell carcinoma of the conjunctiva with excision and postoperative treatment with MMC 0.02% eye drops.