A New Configurable Wireless Sensor System for Biomedical Applications with ISO 18000-3 Interface in 0.35 µm CMOS

• Published in: Sensors (Basel, Switzerland) Vol. 19; no. 19; p. 4110
• Main Authors: Fedtschenko, Tatjana, Utz, Alexander, Stanitzki, Alexander, Hennig, Andreas, Lüdecke, Andre, Haas, Norbert, Kokozinski, Rainer
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23-09-2019; MDPI
• Subjects: 13.56 MHz; amperometry; Antennas; Biomedical materials; Biosensing Techniques - methods; biosensor; Calibration; CMOS; Communication; Data transmission; Digital switching; Electrical measurement; Electrodes; Glucose; ISO 18000-3; NFC; potentiostat; Process controls; Protocol; Receivers & amplifiers; RFID; Sensors; Signal processing; Telemetry - methods; wireless; Wireless communications; Wireless Technology; 13.56 MHz; amperometry; ISO 18000-3; biosensor; RFID; NFC; wireless; potentiostat
• ISSN: 1424-8220; 1424-8220
• DOI: 10.3390/s19194110

This article presents a new configurable wireless sensor system. The system is used to perform amperometric measurements and send the measurement data to a handheld reader using a wireless transponder interface. The two-chip sensor system was implemented in a 0.35 μm CMOS technology. The system consists of an integrated nano-potentiostat that performs the actual measurements and an ISO 18000-3 compliant frontend that enables wireless telemetric data transmission and powering of the entire sensor system. The system was manufactured in combination with a chronoamperometric glucose sensor which allows the measurement of the glucose content in tear fluid and thus a non-invasive determination of the blood sugar level. For a range of sensor currents from 0.1 μA to 10 μA, the potentiostat achieved an accuracy of better than 5 % with a total power dissipation of less than 600 μW. With the realized antenna geometry a wireless communication distance of more than 7 cm has been achieved.