Moyamoya pattern of vascular occlusion after radiotherapy for glioma of the optic chiasm

We studied three children who suffered massive strokes 2 to 5 years after intracranial irradiation of optic chiasm gliomas. Arteriography showed moyamoya changes in all three. CTs showed dramatic reduction in tumor size in two patients, but we believe radiotherapy should only be used sparingly to tr...

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Bibliographic Details
Published in:	Neurology Vol. 36; no. 9; pp. 1173 - 1178
Main Authors:	BEYER, R. A, PADEN, P, SOBEL, D. F, FLYNN, F. G
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Lippincott Williams & Wilkins 01-09-1986
Subjects:	Arterial Occlusive Diseases - diagnostic imaging Biological and medical sciences Cerebral Arteries Child, Preschool Cranial Nerve Neoplasms - radiotherapy Female Glioma - radiotherapy Humans Infant Male Medical sciences Neurology Optic Chiasm Radiography Tumors of the nervous system. Phacomatoses Human Intracranial Nervous system diseases Radiodiagnosis Radiotherapy Optic chiasma Carotid angiography Collateral circulation Glioma Carotid Complication Tumor Child Cerebrovascular disease
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Summary:	We studied three children who suffered massive strokes 2 to 5 years after intracranial irradiation of optic chiasm gliomas. Arteriography showed moyamoya changes in all three. CTs showed dramatic reduction in tumor size in two patients, but we believe radiotherapy should only be used sparingly to treat optic chiasm gliomas in young children, because its efficacy is unproven, and side effects may be catastrophic.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0028-3878 1526-632X
DOI:	10.1212/wnl.36.9.1173