CYTOKINE CONCENTRATIONS IN PEDIATRIC PATIENTS WITH CRIMEAN-CONGO HEMORRHAGIC FEVER

• Published in: The Pediatric infectious disease journal Vol. 33; no. 11; pp. 1185 - 1187
• Main Authors: TEZER, Hasan, OZKAYA-PARLAKAY, Aslinur, KIZILGÜN, Murat, KAYA, Anşnur, GULHAN, Belgin, YÜKSEK, Saliha Kanik, KARA, Soner Sertan, SONMEZER, Meliha Cagla, CEYLANER, Serdar
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01-11-2014
• Subjects: Adolescent; Arboviral haemorrhagic fevers; Arboviroses; Biological and medical sciences; Biomarkers - blood; Case-Control Studies; Child; Child, Preschool; Female; Hemorrhagic Fever, Crimean - blood; Human viral diseases; Humans; Infant; Infectious diseases; Interleukin-10 - blood; Interleukin-6 - blood; Male; Medical sciences; Prognosis; Tropical viral diseases; Tumor Necrosis Factor-alpha - blood; Viral diseases; Human; Pediatrics; Prognosis; Mortality; Cytokine; Congo-Crimean haemorrhagic fever; Concentration; Hemorrhage; Crimean-Congo hemorrhagic fever; Infection; children; Viral disease; Arbovirus disease; Child
• ISSN: 0891-3668; 1532-0987
• DOI: 10.1097/INF.0000000000000398

Crimean-Congo hemorrhagic fever is a zoonotic disease that can be a severe illness in humans. We investigated concentrations of interleukin (IL)-6, tumor necrosis factor-α and IL-10 in serum samples obtained from 25 pediatric Crimean-Congo hemorrhagic fever cases and 35 control children with no signs of infection. Lower cytokine values in our patients could be a good prognostic factor to for a better outcome.