Economic analysis of the supercritical fluid extraction of lupane-triterpenoids from Acacia dealbata Link bark

• Published in: Industrial crops and products Vol. 200; p. 116838
• Main Authors: Rodrigues, Vítor H., Portugal, Inês, Silva, Carlos M.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15-09-2023
• Subjects: Acacia dealbata; Bark; Economic analysis; Lupenyl acetate; Supercritical fluid extraction; Triterpenoids; Economic analysis; Triterpenoids; Supercritical fluid extraction; Bark; Acacia dealbata; Lupenyl acetate
• ISSN: 0926-6690; 1872-633X
• DOI: 10.1016/j.indcrop.2023.116838

The supercritical fluid extraction of Acacia dealbata Link. bark was performed with carbon dioxide at different pressures (10–30 MPa), temperatures (40–80 °C), and cosolvents contents (0–10 wt% of ethyl acetate or ethanol) to analyse their effect on various performance indicators whose best values were: total extraction yield of 1.57 wt%; lupenyl acetate (LA) and lupenone (Lu) extraction yields of 777.5 mg kgbark-1 and 679.8 mg kgbark-1; and LA and Lu extract concentrations of 15.8 wt% and 12.8 wt%. Two extraction curves were measured, and an economic analysis was accomplished. The impact of pressure, temperature, cosolvent content, and extraction time on the cost of manufacturing (COM) and productivity were evaluated, reaching a minimum of 52.3 € kgextract-1. A sensitivity analysis showed that the electricity price is the most impactful variable on the COM. Overall, the increase of pressure, temperature and cosolvents content favoured the productivity, decreasing the production cost.
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•SFE of Acacia dealbata L. bark with CO2 modified or not with ethyl acetate or ethanol.•Studied variables: P (10–30 MPa), T (40–80 °C), cosolvent content (0–10 wt%).•Responses: total extraction yield, lupenyl acetate and lupenone yields & conc.•Two SFE curves measured; 25 SFE experiments performed during 6 h.•Studied cost of manufacturing & productivity: minimum value of 52.3 € kgextract-1.