Synthesis of Some New 1,4-Dihydropyridine Derivatives through a Facile One-pot Hantzsch Condensation Catalyzed by Triethylamine
A facile and efficient synthesis of new 1,4-dihydropyridine derivatives was reported via Hantzsch three-com- ponent condensation reaction of aldehydes or formylphenylboronic acids, ethyl acetoacetate, and ammonium acetate in the presence of a catalytic amount of triethylamine under solvent-free cond...
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Published in: | Chinese journal of chemistry Vol. 30; no. 3; pp. 733 - 737 |
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Main Author: | |
Format: | Journal Article |
Language: | English |
Published: |
Weinheim
WILEY-VCH Verlag
01-03-2012
WILEY‐VCH Verlag Wiley Subscription Services, Inc |
Subjects: | |
Online Access: | Get full text |
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Summary: | A facile and efficient synthesis of new 1,4-dihydropyridine derivatives was reported via Hantzsch three-com- ponent condensation reaction of aldehydes or formylphenylboronic acids, ethyl acetoacetate, and ammonium acetate in the presence of a catalytic amount of triethylamine under solvent-free conditions. The method described here of- fers several advantages including high yields, short reaction times, and simple work-up procedure. |
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Bibliography: | 31-1547/O6 1,4-dihydropyridine, triethylamine, formylphenylboronic acid, Hantzsch reaction, solvent-flee condi-tion A facile and efficient synthesis of new 1,4-dihydropyridine derivatives was reported via Hantzsch three-com- ponent condensation reaction of aldehydes or formylphenylboronic acids, ethyl acetoacetate, and ammonium acetate in the presence of a catalytic amount of triethylamine under solvent-free conditions. The method described here of- fers several advantages including high yields, short reaction times, and simple work-up procedure. istex:3B72C4CA88A72CB27FD8A49D049DA1ED7307936E ArticleID:CJOC201280006 ark:/67375/WNG-ZQ47W229-8 |
ISSN: | 1001-604X 1614-7065 |
DOI: | 10.1002/cjoc.201280006 |