Postoperative Care in Kidney Transplantation: A Comparison Between Controlled and Uncontrolled Donation After Circulatory Death

• Published in: Transplantation proceedings Vol. 50; no. 2; pp. 533 - 535
• Main Authors: Roldán-Reina, Á.J., Egea-Guerrero, J.J., Palomo-López, N., Cuenca-Apolo, D.X., Adriaensens-Pérez, M., Porras-López, M., Ruiz de Azúa-López, Z., Corcia-Palomo, Y., Martín-Villén, L.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-03-2018
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2017.11.058

Recent research in kidney transplantation has revealed differences in the evolution of renal function among patients transplanted from 2 alternative programs for donation after circulatory death (DCD). A retrospective, observational, single-center study was carried out from 2013 to 2016 at a level III hospital intensive care unit (ICU) to assess the progression of kidney recipients after transplants from uncontrolled DCD (uDCD) or controlled DCD (cDCD). The following variables were collected for data analysis: demographics, comorbidities, type of donation, lactate, hemoglobin and glucose levels at ICU admission, creatinine concentration at ICU admission, at-hospital ward transfer, at-hospital discharge, radioisotope imaging results, ICU and in-hospital length of stay, and mortality. There were 87 patients eligible for analysis, 42.5% of which were uDCD recipients. Improvement in kidney function was significantly delayed after uDCD compared with cDCD. A multivariate analysis showed that both uDCD and lactate levels at ICU admission increase the risk of poor outcome after renal transplantation. No deaths were registered in either patient group. Our results suggest that kidney transplantation recipients from uDCD recover renal function at a slower rate than patients transplanted from cDCD, a factor that does not affect mortality.