A case of holoprosencephaly and a little review

AbstractHoloprosencephaly (HPE) is a birth defect that occurs during the first weeks of pregnancy and as a result the prosencephalon does not clearly divide in diencephalon, two halves of the telencephalon and lateral ventricles in the brain of the fetus and, in general, HPE is accompanied by facial...

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Bibliographic Details
Published in:	Human pathology : case reports Vol. 15; pp. 29 - 32
Main Authors:	Castañeyra-Perdomo, Agustín, González-Marrero, Ibrahim, González-Toledo, Juan M, Hernández-Abad, Luis G, Castañeyra-Ruiz, Leandro, Gonzalez-Arnay, Emilio, Carmona-Calero, Emilia M
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-03-2019 Elsevier
Subjects:	Brain malformation Facial defects Holoprosencephaly Human foetus Pathology Brain malformation Human foetus Facial defects Holoprosencephaly
Online Access:	Get full text
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Summary:	AbstractHoloprosencephaly (HPE) is a birth defect that occurs during the first weeks of pregnancy and as a result the prosencephalon does not clearly divide in diencephalon, two halves of the telencephalon and lateral ventricles in the brain of the fetus and, in general, HPE is accompanied by facial defects. There are three main types of holoprosencephaly according to severity; alobar, semi-lobar and lobar. We report here a case that could be defined as a semi-lobar form of HPE with hydrocephalus and scarce facial malformations.
ISSN:	2214-3300 2214-3300
DOI:	10.1016/j.ehpc.2018.10.014