A reversible severe gait disorder

A 53-year-old man was admitted for a 6-month progressive disabling gait disorder, weight loss, and increasing fatigue. Examination revealed a markedly impaired gait and flexion contractures of hips and knees, with limited extension (video 1 at Neurology.org). EMG and whole neuraxis MRI were normal....

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Bibliographic Details
Published in:Neurology Vol. 87; no. 14; p. 1521
Main Authors: Zapata-Wainberg, Gustavo, López Ruiz, Rocío, Fernández González, Elena, Alcántara Miranda, Pilar, Gallego, Mercedes, Ramos-Levi, Ana María, Vivancos, José
Format: Journal Article
Language:English
Published: United States American Academy of Neurology 04-10-2016
Online Access:Get full text
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Summary:A 53-year-old man was admitted for a 6-month progressive disabling gait disorder, weight loss, and increasing fatigue. Examination revealed a markedly impaired gait and flexion contractures of hips and knees, with limited extension (video 1 at Neurology.org). EMG and whole neuraxis MRI were normal. Laboratory workup proved primary adrenal insufficiency (AI) (serum cortisol 2.4 [mu]g/dL, ACTH 513.8 pg/mL). Flexion contractures of the lower limbs[1,2] (FCLL) due to AI was suspected.
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ISSN:0028-3878
1526-632X
DOI:10.1212/WNL.0000000000003190