Liver high performance liquid chromatographic porphyrin profiles in experimental porphyria induced by peroxidizing herbicides

The effect of peroxidizing herbicides on the liver porphyrin content of experimental animals was examined. Mice treated with the herbicide oxadiazon accumulated uroporphyrin and protoporphyrin in the liver. Formesafen-treated mice accumulated uroporphyrin and heptacarboxylic porphyrin.

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Bibliographic Details
Published in:	Biomedical chromatography Vol. 5; no. 5; p. 229
Main Authors:	Krijt, J, Sanitrák, J, Vokurka, M, Janousek, V
Format:	Journal Article
Language:	English
Published:	England 01-09-1991
Subjects:	Animals Chromatography, High Pressure Liquid - methods Disease Models, Animal Herbicides - adverse effects Liver - chemistry Male Mice Mice, Inbred ICR Porphyrias - chemically induced Porphyrias - metabolism Porphyrins - analysis
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Description
Summary:	The effect of peroxidizing herbicides on the liver porphyrin content of experimental animals was examined. Mice treated with the herbicide oxadiazon accumulated uroporphyrin and protoporphyrin in the liver. Formesafen-treated mice accumulated uroporphyrin and heptacarboxylic porphyrin.
ISSN:	0269-3879
DOI:	10.1002/bmc.1130050511