Phenylacetic acid in human cerebrospinal fluid and plasma: selected ion monitoring assay

Phenylacetic acid in human cerebrospinal fluid and plasma: selected ion monitoring assay

Phenylacetic acid has been detected in human cerebrospinal fluid and plasma. Free acid and total acid values obtained after hydrolysis have been quantified as the pentafluorobenzyl ester by selected ion monitoring, using [2H7]phenylacetic acid as internal standard.

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Bibliographic Details
Published in:Biomedical mass spectrometry Vol. 5; no. 8; p. 508
Main Authors: Fellows, L E, King, G S, Pettit, B R, Goodwin, B L, Ruthven, C R, Sandler, M
Format: Journal Article
Language:English
Published: England 01-08-1978
Subjects:
Adult
Chromatography, Gas
Humans
Hydrolysis
Mass Spectrometry
Methods
Phenylacetates - analysis
Phenylacetates - blood
Phenylacetates - cerebrospinal fluid
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Description
Summary:Phenylacetic acid has been detected in human cerebrospinal fluid and plasma. Free acid and total acid values obtained after hydrolysis have been quantified as the pentafluorobenzyl ester by selected ion monitoring, using [2H7]phenylacetic acid as internal standard.
ISSN:0306-042X
DOI:10.1002/bms.1200050809