Effect of Far Infrared Drying on Antioxidant Property, Anti-inflammatory Activity, and Inhibitory Activity in A549 Cells of Gamguk (Chrysanthemum indicum L.) Flower

• Published in: Food science and biotechnology Vol. 21; no. 1; pp. 261 - 265
• Main Authors: Kim, W.W., Kangwon National University, Chuncheon, Republic of Korea, Ghimeray, Amal Kumar, Kangwon National University, Chuncheon, Republic of Korea, Wu, J.C., Kangwon National University, Chuncheon, Republic of Korea, Eom, S.H., Kyung Hee University, Yongin, Republic of Korea, Lee, B.G., Korea Energy Technology, Seoul, Republic of Korea, Kang, W.S., Kangwon National University, Chuncheon, Republic of Korea, Cho, D.H., Kangwon National University, Chuncheon, Republic of Korea
• Format: Journal Article
• Language: English
• Published: Heidelberg The Korean Society of Food Science and Technology 01-02-2012; 한국식품과학회
• Subjects: A549; anti-inflammatory; Antiinflammatory agents; Antioxidants; Antitumor activity; Cell proliferation; Chemistry; Chemistry and Materials Science; Chrysanthemum; Data processing; Drying; far infrared ray; Flavonoids; Flowers; Food Science; gamguk; Lipopolysaccharides; Lung cancer; Nitric oxide; Nutrition; phenolic compounds; POLIFENOLES; POLYPHENOL; POLYPHENOLS; Prostaglandin E2; Prostaglandin-endoperoxide synthase; Research Note; Shade; Tumors; 식품과학; (; anti-inflammatory; L.; far infrared ray; polyphenol; A549
• ISSN: 1226-7708; 2092-6456
• DOI: 10.1007/s10068-012-0034-0

This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E₂ (PGE₂) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p less than 0.05) higher in dose and time dependent manner.