A Web-based Dose-volume Histogram Dashboard for Library-based Individualized Dose-constraints and Clinical Plan Evaluation

• Published in: Journal of medical systems Vol. 45; no. 6; p. 62
• Main Authors: Mallick, Indranil, Saha, Saheli, Arunsingh, Moses A
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-06-2021; Springer Nature B.V
• Subjects: Applications programs; Dashboards; Health Informatics; Health Sciences; Histograms; Libraries; Medicine; Medicine & Public Health; Organs; Patients; Planning; Prostate cancer; Prototypes; Radiation; Radiation therapy; Statistics for Life Sciences; Systems-Level Quality Improvement; Treatment planning; Web-based dashboard; dose-volume histogram; Radiation therapy
• ISSN: 0148-5598; 1573-689X
• DOI: 10.1007/s10916-021-01740-9

Traditional methods of treatment planning and plan evaluation involve the use of generic dose-constraints. We aimed to build a web-based application to generate individualized dose-constraints and plan evaluation against a library of prior approved plan dose-volume histograms (DVH).
A prototype was built for intensity modulated radiation therapy (IMRT) plans for prostate cancer. Using exported DVH files from the Varian and Accuray treatment planning systems, a library of plan DVHs was built by data extraction. Given structure volumes of a patient to be planned, a web based application was built to derive individual dose-constraints of the planning target volume (PTV) and organs-at-risk (OAR) based on achieved doses in a library of prior approved plans with similar anatomical volumes, selected using an interactive dashboard. A second web application was built to compare the achieved DVHs of the newly created plan against a library of plans of similar patients.
These web application prototypes are a proof of principle that simple freely available tools can be built for library based planning and review.