Facile microwave-assisted green synthesis of NiO nanoparticles from Andrographis paniculata leaf extract and evaluation of their photocatalytic and anticancer activities

• Published in: Molecular Crystals and Liquid Crystals Vol. 673; no. 1; pp. 70 - 80
• Main Authors: Karthik, K., Shashank, M., Revathi, V., Tatarchuk, Tetiana
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis 22-09-2018; Taylor & Francis Ltd
• Subjects: Andrographis paniculata; Anticancer properties; Breast cancer; Crystallites; HRTEM with SAED; Luminescence; Nanoparticles; Nickel; Nickel oxides; NiO; Photocatalytic and Anticancer activity; Photodegradation; Plant extracts; VSM
• ISSN: 1542-1406; 1563-5287; 1527-1943
• DOI: 10.1080/15421406.2019.1578495

In the present work, NiO nanoparticles based on Andrographis paniculata (leaf extract) were prepared through the microwave-assisted method. The obtained nanoparticles were analyzed using XRD, FTIR, SEM with EDS, HRTEM, UV-Vis and luminescence studies. XRD exhibits cubic structure with an average crystallite size of 24 nm. The vibrational stretching mode of nickel oxygen bond is observed at 470 cm
−1
. The optical energy bandgap value of NiO nanoparticles is found to be 3.51 eV. The luminescence emission peaks observed at 350, 439, 485, and 530 nm. Further, the photodegradation (Evans blue) of prepared nanoparticles was assessed. Anti-breast cancer activity of the prepared nanoparticles was tested against the MCF-7 cell line.