Risk factors of dumping syndrome after fundoplication for gastroesophageal reflux in children

• Published in: Pediatric surgery international Vol. 37; no. 2; pp. 183 - 189
• Main Authors: Yamoto, Masaya, Fukumoto, Koji, Takahashi, Toshiaki, Miyake, Hiromu, Nakaya, Kengo, Nomura, Akiyoshi, Sekioka, Akinori, Yamada, Yutaka, Urushihara, Naoto
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01-02-2021; Springer Nature B.V
• Subjects: Age; Dumping syndrome; Medicine; Medicine & Public Health; Original Article; Ostomy; Pediatric Surgery; Pediatrics; Risk factors; Scoliosis; Surgery; Fundoplication; Dumping syndrome; Microgastria; Scoliosis
• ISSN: 0179-0358; 1437-9813
• DOI: 10.1007/s00383-020-04783-0

Purpose
In postoperative cases of fundoplication, the gastric emptying ability is promoted and sometimes exhibits dumping syndrome. Dumping syndrome often goes unrecognized in children. Furthermore, the risk factors for postoperative dumping syndrome are unknown. This study aimed to investigate the risk factors of developing dumping syndrome after fundoplication.
Methods
A retrospective chart review of all consecutive patients between January 2003 and March 2018 (190 patients) who had fundoplication at our clinic was conducted. Regarding the risk factors of dumping syndrome, gender, age and body weight at the time of surgery, neurological impairment, severe scoliosis, microgastria, chromosomal abnormalities, complex cardiac anomalies, gastrostomy, and laparoscopic surgery were retrospectively studied.
Results
17 patients (9%) developed dumping syndrome post-operatively. Multivariate analysis showed that significant risk factors for dumping syndrome included: undergoing surgery within 12 months of age (adjusted OR 10.3, 95% CI 2.6–45.2), severe scoliosis (adjusted OR 19.3, 95% CI 4.4–91.1), and microgastria (adjusted OR 26.5, 95% CI 1.4–896.4).
Conclusions
We identified that: age at fundoplication being within 12 months of age, severe scoliosis, and microgastria were risk factors for dumping syndrome after fundoplication, and that this information should be explaining to the family before conducting the fundoplication.