A novel mycovirus infecting Aspergillus nidulans that is closely related to viruses in a new genus of the family Partitiviridae

• Published in: Archives of virology Vol. 166; no. 2; pp. 659 - 664
• Main Authors: Jiang, Yinhui, Yang, Bi, Liu, Jiayu, Wang, Qinrong, Zhang, Qifang, Yu, Wenfeng, Hsiang, Tom
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01-02-2021; Springer Nature B.V
• Subjects: Amino Acid Sequence; Annotated Sequence Record; Aspergillus nidulans; Aspergillus nidulans - virology; Base Sequence; Biomedical and Life Sciences; Biomedicine; Capsid protein; Capsid Proteins - genetics; DNA-directed RNA polymerase; Double-stranded RNA; Fungal Viruses - genetics; Fungi; Genome, Viral - genetics; Genomes; Infectious Diseases; Medical Microbiology; New genera; Open reading frames; Open Reading Frames - genetics; Partitiviridae; Phylogeny; RNA polymerase; RNA Viruses - genetics; RNA, Double-Stranded - genetics; RNA, Viral - genetics; RNA-Dependent RNA Polymerase - genetics; RNA-directed RNA polymerase; Sequence Analysis, DNA - methods; Virology
• ISSN: 0304-8608; 1432-8798
• DOI: 10.1007/s00705-020-04930-x

The bisegmented genome of a novel double-stranded (ds) RNA mycovirus, named “Aspergillus nidulans partitivirus 1” (AnPV1), isolated from the fungus
Aspergillus nidulans
strain HJ5-47, was sequenced and analyzed. AnPV1 contains two segments, AnPV1-1 and AnPV1-2. AnPV1-1 has 1837 bp with an open reading frame (ORF) that potentially encodes a putative RNA-dependent RNA polymerase (RdRp) of 572 amino acids (aa). AnPV1-2 has 1583 bp with an ORF encoding a putative capsid protein (CP) of 488 aa. Phylogenetic analyses indicated that AnPV1 and related viruses clustered in a group that could represent a new unclassified genus in the family
Partitiviridae
.