Characterization of adrenal masses with chemical shift and gadolinium-enhanced MR imaging

To assess the potential role of chemical shift and dynamic gadolinium-enhanced magnetic resonance (MR) imaging in the characterization of adrenal masses. Fifty-one adrenal masses (35 adenomas and 16 nonadenomas) in 43 patients were evaluated with chemical shift MR imaging, dynamic gadolinium-enhance...

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Bibliographic Details
Published in:Radiology Vol. 197; no. 2; p. 411
Main Authors: Korobkin, M, Lombardi, T J, Aisen, A M, Francis, I R, Quint, L E, Dunnick, N R, Londy, F, Shapiro, B, Gross, M D, Thompson, N W
Format: Journal Article
Language:English
Published: United States 01-11-1995
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Summary:To assess the potential role of chemical shift and dynamic gadolinium-enhanced magnetic resonance (MR) imaging in the characterization of adrenal masses. Fifty-one adrenal masses (35 adenomas and 16 nonadenomas) in 43 patients were evaluated with chemical shift MR imaging, dynamic gadolinium-enhanced MR imaging, or both. The relative change in the signal intensity (SI) ratio of the adrenal mass to liver and paraspinal muscles was quantitatively and qualitatively assessed. Opposed-phase gradient-echo (GRE) images were compared with in-phase images. With qualitative visual inspection, only adenomas showed a decrease in relative SI ratio on opposed-phase chemical shift images (specificity, 100%; sensitivity, 81%). Quantitative ratios corresponding to 100% specificity were also observed, with similar sensitivities. Adenomas could not be differentiated from nonadenomas with visual assessment of maximum SI after contrast material administration or washout. Characterization of an adrenal mass as an adenoma can be made with high specificity and acceptable sensitivity by visually comparing opposed-phase with in-phase GRE images.
ISSN:0033-8419
DOI:10.1148/radiology.197.2.7480685