Dose characteristics of radachlorin photosensitizer in modeling the photodynamic effect on the cellular level

Dose characteristics of radachlorin photosensitizer in modeling the photodynamic effect on the cellular level

A study was carried out on the dose characteristics of the Radachlorin photosensitizer using both a laser light source and partially coherent irradiation from a matrix light-emitting diode observing the photodynamic effect on an erythrocyte suspension at various concentrations. The use of these resu...

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Published in:Measurement techniques Vol. 54; no. 12; pp. 1412 - 1420
Main Authors: Zhorina, L. V., Zalevskaya, L. I., Zalevskaya, O. I., Zmievskoi, G. N., Semchuk, I. P., Filatov, V. V.
Format: Journal Article
Language:English
Published: Boston Springer US 01-03-2012
Springer
Springer Nature B.V
Subjects:
Analytical Chemistry
Aqueous solutions
Blood substitutes
Cellular
Cellular biology
Characterization and Evaluation of Materials
Chlorophyll
Coherence
Dosimetry
Erythrocytes
Experiments
Irradiation
Lasers
Light
Light sources
Light-emitting diodes
Measurement Science and Instrumentation
Measurement techniques
Medical research
Photodynamic therapy
Physical Chemistry
Physics
Physics and Astronomy
Sensors
Studies
effectiveness
pulse regime
Radachlorin
photodynamic effect
threshold dose
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Abstract A study was carried out on the dose characteristics of the Radachlorin photosensitizer using both a laser light source and partially coherent irradiation from a matrix light-emitting diode observing the photodynamic effect on an erythrocyte suspension at various concentrations. The use of these results is proposed for developing a procedure for the a priori determination of irradiation dose for specific patients in the course of photodynamic therapy.
AbstractList A study was carried out on the dose characteristics of the Radachlorin photosensitizer using both a laser light source and partially coherent irradiation from a matrix light-emitting diode observing the photodynamic effect on an erythrocyte suspension at various concentrations. The use of these results is proposed for developing a procedure for the a priori determination of irradiation dose for specific patients in the course of photodynamic therapy.[PUBLICATION ABSTRACT]
A study was carried out on the dose characteristics of the Radachlorin photosensitizer using both a laser light source and partially coherent irradiation from a matrix light-emitting diode observing the photodynamic effect on an erythrocyte suspension at various concentrations. The use of these results is proposed for developing a procedure for the a priori determination of irradiation dose for specific patients in the course of photodynamic therapy.
A study was carried out on the dose characteristics of the Radachlorin photosensitizer using both a laser light source and partially coherent irradiation from a matrix light-emitting diode observing the photodynamic effect on an erythrocyte suspension at various concentrations. The use of these results is proposed for developing a procedure for the a priori determination of irradiation dose for specific patients in the course of photodynamic therapy. Keywords: photodynamic effect, Radachlorin, threshold dose, pulse regime, effectiveness.
Audience Academic
Author Filatov, V. V.
Zalevskaya, L. I.
Zhorina, L. V.
Zmievskoi, G. N.
Zalevskaya, O. I.
Semchuk, I. P.
Author_xml – sequence: 1
  givenname: L. V.
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  organization: Bauman Moscow State Technical University
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  givenname: L. I.
  surname: Zalevskaya
  fullname: Zalevskaya, L. I.
  organization: Rada-Pharma Company
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  givenname: O. I.
  surname: Zalevskaya
  fullname: Zalevskaya, O. I.
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  givenname: G. N.
  surname: Zmievskoi
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  email: zmievskoy@mail.ru
  organization: Bauman Moscow State Technical University
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  surname: Semchuk
  fullname: Semchuk, I. P.
  organization: Bauman Moscow State Technical University
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  givenname: V. V.
  surname: Filatov
  fullname: Filatov, V. V.
  organization: Bauman Moscow State Technical University
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Cites_doi 10.1039/b817175k
10.1117/12.379889
ContentType Journal Article
Copyright Springer Science+Business Media, Inc. 2012
COPYRIGHT 2012 Springer
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Issue 12
Keywords effectiveness
pulse regime
Radachlorin
photodynamic effect
threshold dose
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– volume-title: Molecular Biophysics Physics of Life Processes [in Russian]
  year: 1975
  ident: 9904_CR21
  contributor:
    fullname: MV Volkenshtein
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Snippet A study was carried out on the dose characteristics of the Radachlorin photosensitizer using both a laser light source and partially coherent irradiation from...
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SubjectTerms Analytical Chemistry
Aqueous solutions
Blood substitutes
Cellular
Cellular biology
Characterization and Evaluation of Materials
Chlorophyll
Coherence
Dosimetry
Erythrocytes
Experiments
Irradiation
Lasers
Light
Light sources
Light-emitting diodes
Measurement Science and Instrumentation
Measurement techniques
Medical research
Photodynamic therapy
Physical Chemistry
Physics
Physics and Astronomy
Sensors
Studies
Title Dose characteristics of radachlorin photosensitizer in modeling the photodynamic effect on the cellular level
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Volume 54
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