Intracytoplasmic sperm injection outcomes of obstructive and nonobstructive azoospermic men

• Published in: Archives of gynecology and obstetrics Vol. 288; no. 3; pp. 683 - 686
• Main Authors: Celikten, Ayse, Batioglu, Sertac, Gungor, Ayse Nur Cakir, Ozdemir, Erkan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01-09-2013; Springer Nature B.V
• Subjects: Adult; Azoospermia; Endocrinology; Female; Fertility; Gynecology; Health risk assessment; Human Genetics; Humans; Male; Medicine; Medicine & Public Health; Obstetrics/Perinatology/Midwifery; Pregnancy; Pregnancy Rate; Reproductive Medicine; Retrospective Studies; Sperm; Sperm Injections, Intracytoplasmic; Obstructive azoospermia; Nonobstructive azoospermia; Intracytoplasmic sperm injection
• ISSN: 0932-0067; 1432-0711
• DOI: 10.1007/s00404-013-2799-7

Purpose
We aimed to compare the outcomes of intracytoplasmic sperm injection (ICSI) cycles in ostructive and nonobstructive azoospermic men.
Methods
In this retrospective study, we searched the first ICSI cycle parameters of 211 azoospermic men. Our main outcomes were the average fertilization rate, implantation rate, pregnancy and miscarriage rates.
Results
The results of this study showed that although the males with obstructive azoospermia had better fertilization and biochemical pregnancy rates than the ones with nonobstructive azoospermia, clinical pregnancy and miscarriage rates among the groups were similar.
Conclusion
ICSI overcomes the obstacles related to the sperm in its function as a carrier but it cannot alter the message carried by the male gamete.