Neural plasticity in developing and adult olfactory pathways – focus on the human olfactory bulb

• Published in: Journal of bioenergetics and biomembranes Vol. 51; no. 1; pp. 77 - 87
• Main Authors: Huart, C., Rombaux, Ph, Hummel, T.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-02-2019; Springer Nature B.V
• Subjects: Animal Anatomy; Animal Biochemistry; Biochemistry; Bioorganic Chemistry; Chemistry; Chemistry and Materials Science; Histology; Humans; Magnetic resonance imaging; Mini-Review; Morphology; Neural plasticity; Neurogenesis; Neuronal Plasticity - physiology; NMR; Nuclear magnetic resonance; Olfactory bulb; Olfactory Bulb - physiology; Olfactory pathways; Olfactory Pathways - physiology; Olfactory system; Organic Chemistry; Plastic foam; Smell; Anosmia; Nose; Neuroregeneration; Plasticity; Smell
• ISSN: 0145-479X; 1573-6881
• DOI: 10.1007/s10863-018-9780-x

The topic of human adult neural plasticity and neurogenesis is of great interest for medical and scientific community, but it is also largely debated. In the last years, an increasing interest has been paid to the olfactory system, and particularly to the plasticity of the olfactory bulb (OB). While the molecular/cellular mechanisms underlying OB plasticity remain a matter of debate, measurements of the OB using magnetic resonance imaging clearly indicate that it is a highly plastic structure. In this review, we present results regarding the plasticity of the human adult olfactory system.