National outcomes of laparoscopic Heller myotomy: operative complications and risk factors for adverse events

• Published in: Surgical endoscopy Vol. 29; no. 11; pp. 3097 - 3105
• Main Authors: Ross, Samuel W., Oommen, Bindhu, Wormer, Blair A., Walters, Amanda L., Matthews, Brent D., Heniford, B. T., Augenstein, Vedra A.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-11-2015; Springer Nature B.V
• Subjects: Abdominal Surgery; Adult; Aged; Alcohol use; Body mass index; Data collection; Databases, Factual; Endoscopy; Esophageal Achalasia - surgery; Esophagus; Female; Gastroenterology; Gynecology; Hepatology; Humans; Incidence; Laparoscopy; Length of Stay - statistics & numerical data; Logistic Models; Male; Medicine; Medicine & Public Health; Middle Aged; Morbidity; Operative Time; Patients; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Proctology; Quality improvement; Radiation therapy; Reoperation; Risk Factors; Surgery; Surgical outcomes; Treatment Outcome; United States; United States; United States > US; Heller myotomy; Achalasia; Intra-operative EGD; Laparoscopic Heller myotomy; Complications; Myotomy
• ISSN: 0930-2794; 1432-2218
• DOI: 10.1007/s00464-014-4054-0

Introduction
Laparoscopic Heller myotomy (LHM) has supplanted an open approach due to decreased operative morbidity. Our goal was to quantify the incidence of peri-operative complications and identify risk factors for adverse outcomes in LHM.
Methods
All LHM were queried from 2005 to 2011 from the National Surgical Quality Improvement Program database. Adverse outcomes were identified, and univariate and stepwise logistic regression (MVR) was then performed to quantify association.
Results
There were 1,237 LHM in the study period. Patient averages were: age 51.9 ± 16.8 years, BMI 27.3 ± 6.6 kg/m
2
, Charlson comorbidity index (CCI) 0.2 ± 0.6. 15.3 % had >10 % body mass loss in the preoperative 6 months. During surgery, 10.2 % underwent concomitant EGD, and mean operative time was 141.6 ± 63.4 min. There were 7(0.06 %) wound complications, 22(1.8 %) general complications, and 30(2.4 %) major complications. Average length of stay (LOS) was 2.8 ± 5.5 days. The rate of readmission and reoperation were 3.1 and 2.3 %, respectively, and there were 4(0.03 %) deaths. General and major complications were associated with alcohol use, pack-years of smoking, weight loss, history of stroke, radiation therapy, and longer operative times (
p
 < 0.05); however, these factors did not remain significant on MVR (
p
 > 0.05). Operative time was found to be significantly longer by 35.3 min for inpatients, 43.1 min in functionally dependent patients, 50.0 min in preoperative septic patients, and 17.2 min with concomitant EGD (
p
 < 0.01 for all). LOS was found to be longer by 1.9 days for inpatients, 1.8 days in ASA category ≥3, and 1.2 days per one point increase in CCI (
p
 < 0.001 for all).
Conclusion
LHM is being performed nationally with a low incidence of operative complications and mortality. General and major complications following LHM are associated with patient alcohol use, pack-years of smoking, weight loss, history of stroke, radiation therapy, and longer operative times. Additionally, independent predictors of longer operative time and LOS were identified.