Expression of Bruton’s tyrosine kinase in B-cell neoplasms evaluated by flow cytometry

Bruton’s tyrosine kinase (BTK) is a cytoplasmatic protein that is part of the B-cell antigen receptor signaling pathway. Our aim was to evaluate the expression of BTK in B-cell neoplasms and compare it to normal B-cell lymphocytes. After surface staining with CD19 and CD45, flow cytometry staining f...

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Bibliographic Details
Published in:	Clinical and experimental medicine Vol. 17; no. 4; pp. 499 - 504
Main Authors:	Marcondes, Natália Aydos, Fernandes, Flavo Beno, Alegretti, Ana Paula, Faulhaber, Gustavo Adolpho Moreira
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01-11-2017 Springer Nature B.V
Subjects:	Adolescent Adult Aged Aged, 80 and over Female Flow Cytometry Hematology Humans Internal Medicine Kinases Lymphoma, B-Cell - pathology Male Medicine Medicine & Public Health Middle Aged Oncology Original Article Protein-Tyrosine Kinases - analysis T cell receptors Tumors Young Adult B-cell neoplasm BTK Bruton’s tyrosine kinase Flow cytometry
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