Isolated Spleen Metastases of Endometrial Cancer: A Case Report

• Published in: Medicina (Kaunas, Lithuania) Vol. 58; no. 5; p. 592
• Main Authors: Stojanovic, Marko M, Brzački, Vesna, Zivadinovic, Jelena D, Ignjatovic, Nebojsa S, Gmijovic, Marko D, Djordjevic, Miodrag N, Golubovic, Ilija, Nikolić, Nada G, Bojanic, Novica Z, Stojanovic, Miroslav P
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26-04-2022; MDPI
• Subjects: Abdomen; Antigens; Biomarkers; cancer; Cancer therapies; Case Report; Case reports; Chemotherapy; endometrial; Endometrial cancer; Endometrial Neoplasms - pathology; Female; Hematology; Humans; Hypotheses; Hysterectomy; Laboratories; Laparoscopy; Magnetic resonance imaging; Medical prognosis; metastases; Metastasis; Neoplasms, Second Primary; Ovarian cancer; Patients; Spleen; Splenectomy; Splenic Neoplasms - secondary; Splenic Neoplasms - surgery; Surgery; Tomography; Tumors; Ultrasonic imaging; Uterus; metastases; cancer; endometrial; spleen; splenectomy
• ISSN: 1648-9144; 1010-660X; 1648-9144
• DOI: 10.3390/medicina58050592

Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature.
We report a patient with isolated splenic metastases of endometrial cancer 3 years after radical surgery of the primary tumor. The patient was successfully treated by splenectomy and six cycles of paclitaxel. Fifty months after splenectomy, she was alive and well, and with no evidence of disease.
Isolated spleen metastasis of endometrial cancer is very rare. Radical surgery and adjuvant therapy may offer excellent long-term survival.