Antibiotic resistance: challenges and successes in respiratory infection

• Published in: Future microbiology Vol. 11; no. 4; pp. 481 - 484
• Main Authors: Sethi, Sanjay, Bryan, Jenny
• Format: Journal Article Conference Proceeding
• Language: English
• Published: England Future Medicine Ltd 01-01-2016
• Subjects: Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; antibiotics; antimicrobial resistance; Clinical Trials as Topic; Community-Acquired Infections - drug therapy; Community-Acquired Infections - microbiology; Cross Infection - drug therapy; Cross Infection - microbiology; Drug Resistance, Bacterial; Drug Therapy - methods; Global Health; Humans; Pneumonia, Bacterial - drug therapy; Pneumonia, Bacterial - microbiology; respiratory infections; antimicrobial resistance; antibiotics; respiratory infections
• ISSN: 1746-0913; 1746-0921
• DOI: 10.2217/fmb-2016-0006

With approximately 50,000 deaths in the US and EU attributed to antibacterial resistance each year, together with several million days of hospital care [
], the need to address resistance mechanisms and find new targets for novel antibiotics has never been greater. At the annual congresses of the European Respiratory Society and the American College of Chest Physicians, presenters reported advances in understanding of the mechanisms of antibiotic resistance and how these may be overcome. The latest clinical trial data on antibiotic treatment for hospital- and community-acquired pneumonia, including the potential for novel nebulized forms of therapy, were also discussed.