Passive Immune Elimination and in Vitro Phagocytosis of Antigen-Antibody Complexes in Relation to Species Origin of Antibody

The initial rate of passive immune elimination of a soluble antigen by antiserum was dependent on the species source of the antiserum. Rabbit antiserum resulted in rapid passive immune elimination in rodents and birds. Avian antiserum produced passive elimination in birds but not guinea pigs and rab...

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Bibliographic Details
Published in:	The Journal of immunology (1950) Vol. 97; no. 1; pp. 138 - 149
Main Authors:	Patterson, Roy, Suszko, Irena M
Format:	Journal Article
Language:	English
Published:	United States Am Assoc Immnol 01-07-1966
Subjects:	Animals Antigen-Antibody Reactions Guinea Pigs In Vitro Techniques Phagocytosis Poultry Rabbits Serum Albumin, Bovine Species Specificity Spleen - cytology
Online Access:	Get full text
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Summary:	The initial rate of passive immune elimination of a soluble antigen by antiserum was dependent on the species source of the antiserum. Rabbit antiserum resulted in rapid passive immune elimination in rodents and birds. Avian antiserum produced passive elimination in birds but not guinea pigs and rabbits. The results, confirmed by in vitro studies, appeared independent of complement. They suggest a specific recognition system of immunoglobulin structure by phagocytic cells.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0022-1767 1550-6606
DOI:	10.4049/jimmunol.97.1.138