Facile Diastereoselective Synthesis of Carbohydrate-Based Thiochromans

Facile Diastereoselective Synthesis of Carbohydrate-Based Thiochromans

An efficient and novel diastereoselective thiochroman synthesis using the carbohydrate chiral pool via intramolecular Friedel-Crafts alkylation is presented. The scope and limitations of the method are investigated.

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Bibliographic Details
Published in:Journal of carbohydrate chemistry Vol. 32; no. 2; pp. 139 - 157
Main Authors: Kinfe, Henok H., Moshapo, Paseka T., Makolo, Felix L., Muller, Alfred
Format: Journal Article
Language:English
Published: Philadelphia Taylor & Francis Group 12-02-2013
Taylor & Francis Ltd
Subjects:
Alkylation
Carbohydrate
Carbohydrates
Friedel-Crafts Alkylation
Thiochroman
Online Access:Get full text
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Description
Summary:An efficient and novel diastereoselective thiochroman synthesis using the carbohydrate chiral pool via intramolecular Friedel-Crafts alkylation is presented. The scope and limitations of the method are investigated.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0732-8303
1532-2327
DOI:10.1080/07328303.2012.762103