Maternal Garlic Oil Supplementation Prevents High‐Fat Diet‐Induced Hypertension in Adult Rat Offspring: Implications of H2S‐Generating Pathway in the Gut and Kidneys

Scope Perinatal high‐fat (HF) diet induces hypertension in adult offspring. Garlic, a naturally dietary source of Hydrogen sulfide (H2S) donor, has been shown benefits in hypertension. The article examines whether maternal garlic oil supplementation can prevent hypertension induced by HF diet and el...

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Bibliographic Details
Published in:	Molecular nutrition & food research Vol. 65; no. 11; pp. e2001116 - n/a
Main Authors:	Hsu, Chien‐Ning, Hou, Chih‐Yao, Chang‐Chien, Guo‐Ping, Lin, Sufan, Tain, You‐Lin
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01-06-2021
Subjects:	Animals Bioavailability Body Weight - drug effects Breastfeeding & lactation developmental origins of health and disease (DOHaD) Diet Diet, High-Fat - adverse effects Dietary Supplements Fatty acids Fatty Acids, Volatile - metabolism Female Garlic Garlic - chemistry Gastrointestinal Microbiome - drug effects Gastrointestinal Microbiome - physiology Gene expression gut microbiota High fat diet Hydrogen sulfide Hydrogen Sulfide - blood Hydrogen Sulfide - metabolism Hypertension Hypertension - etiology Hypertension - prevention & control Intestinal microflora Kidney - drug effects Kidney - metabolism Kidneys Lactation Male Males Metabolites Microbiota Offspring Oil Oils & fats Plant Oils - chemistry Plant Oils - pharmacology Pregnancy Prenatal Exposure Delayed Effects Rats Rats, Sprague-Dawley short chain fatty acid garlic developmental origins of health and disease (DOHaD) hydrogen sulfide high-fat diet hypertension gut microbiota short chain fatty acid
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