A 44-year-old stone worker with progressive dyspnea: lessons from a new twist on an old foe

• Published in: Monaldi archives for chest disease Vol. 93; no. 2
• Main Authors: Manglani, Ravi, Akbar, Sara, Beasley, Mary Beth, Epelbaum, Oleg
• Format: Journal Article
• Language: English
• Published: Italy PAGEPress Publications 13-09-2022
• Subjects: acute silicosis; Adult; Artificial stone worker; Dyspnea - diagnosis; Dyspnea - etiology; Humans; Occupational Exposure - adverse effects; Occupations; Silicon Dioxide; silicoproteinosis; silicosis; Silicosis - diagnosis; Silicosis - diagnostic imaging; whole lung lavage
• ISSN: 1122-0643; 2532-5264
• DOI: 10.4081/monaldi.2022.2345

Silicosis is typically an indolent lung disease caused by long-standing occupational exposure to respirable crystalline silica, classically in professions such as sandblasting and mining.  An increasingly popular industry that has earned particular interest because of its association with silicosis is customization and installation of artificial stone countertops for domestic applications. In addition to causing a spike in cases of chronic and accelerated silicosis, both quite familiar to respiratory clinicians, outbreaks of artificial stone silicosis have brought to the fore a historically rare entity known as acute silicosis, or silicoproteinosis, a more rapid presentation of the disease. Failure to suspect this uncommon condition can lead to diagnostic confusion and therefore ineffective treatment as was true initially of the patient we describe herein.  The case description is followed by a clinical, radiological, and pathological overview of acute artificial stone silicosis (or silicoproteinosis), which is an emerging pneumoconiosis with sparse coverage in the literature to date.  This case also adds to the few existing reports on the use of therapeutic whole lung lavage for silicoproteinosis.