High-throughput experimentation in synthetic polymer chemistry: From RAFT and anionic polymerizations to process development

• Published in: Applied surface science Vol. 252; no. 7; pp. 2555 - 2561
• Main Authors: Guerrero-Sanchez, Carlos, Paulus, Renzo M., Fijten, Martin W.M., de la Mar, Mariska J., Hoogenboom, Richard, Schubert, Ulrich S.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier B.V 31-01-2006; Elsevier Science
• Subjects: Anionic polymerization; Applied sciences; Combinatorial material research; Exact sciences and technology; Free radical polymerization; High-throughput experimentation; Organic polymers; Physicochemistry of polymers; Polymer reactions and polymerization; Properties and characterization; RAFT polymerization; Free radical polymerization; 81.20.-n; 87.15.Rn; High-throughput experimentation; Combinatorial material research; Anionic polymerization; RAFT polymerization; 82.35.-x; Combinatorial method; 87.15.Rn High-throughput experimentation; Polymer; Free radical; Fragmentation
• ISSN: 0169-4332; 1873-5584
• DOI: 10.1016/j.apsusc.2005.05.088

The application of combinatorial and high-throughput approaches in polymer research is described. An overview of the utilized synthesis robots is given, including different parallel synthesizers and a process development robot. In addition, the application of the parallel synthesis robots to reversible addition fragmentation termination (RAFT) radical polymerizations and ionic copolymerizations is overviewed. Moreover, first results concerning the process development of semi-batch free radical polymerizations are described.