Nanostarch Reinforced with Chitosan/Poly (vinyl pyrrolidone) Blend for In Vitro Wound Healing Application

Nanostarch Reinforced with Chitosan/Poly (vinyl pyrrolidone) Blend for In Vitro Wound Healing Application

Nanostarch, which is inexpensive and environmentally abundant, has been used as filler to prepare biocompatible films. The bio-nanocomposites were synthesized by solution casting method. TEM analysis proves that the average particle size of the nanostarch is in the range of 20-40 nm. Thermal stabili...

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Bibliographic Details
Published in:Polymer-plastics technology and engineering Vol. 57; no. 14; pp. 1400 - 1410
Main Authors: Poonguzhali, R., Basha, S. Khaleel, Kumari, V. Sugantha
Format: Journal Article
Language:English
Published: New York Taylor & Francis 22-09-2018
Taylor & Francis Ltd
Subjects:
Biocompatibility
Chitosan
cytotoxicity
Nanocomposites
nanostarch
poly (vinyl pyrrolidone)
Pseudomonas aeruginosa
Synergistic effect
Thermal stability
Wound healing
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Summary:Nanostarch, which is inexpensive and environmentally abundant, has been used as filler to prepare biocompatible films. The bio-nanocomposites were synthesized by solution casting method. TEM analysis proves that the average particle size of the nanostarch is in the range of 20-40 nm. Thermal stability and cell viability of CS/PVP matrix were best enhanced at 1% of nanostarch loading. The antibacterial activity exhibited by CPS bio-nanocomposite against Staphylococcus aureus and Pseudomonas aeruginosa and synergistic effects of CPS such as barrier properties, swelling properties, and better blood compatibility make it a suitable material for in vitro wound healing application.
ISSN:0360-2559
1525-6111
DOI:10.1080/03602559.2017.1381255