Synthesis of silver nanoparticles from Bacillus brevis (NCIM 2533) and their antibacterial activity against pathogenic bacteria

• Published in: Microbial pathogenesis Vol. 116; pp. 221 - 226
• Main Authors: Saravanan, Muthupandian, Barik, Sisir Kumar, MubarakAli, Davoodbasha, Prakash, Periyakaruppan, Pugazhendhi, Arivalagan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-03-2018
• Subjects: Antimicrobial activity; Bacillus brevis; Biosynthesis; Human pathogen; Multi-drug resistant; Silver nanoparticles; Bacillus brevis; Multi-drug resistant; Antimicrobial activity; Biosynthesis; Human pathogen; Silver nanoparticles
• ISSN: 0882-4010; 1096-1208
• DOI: 10.1016/j.micpath.2018.01.038

The present study is focused on the biological synthesis of silver nanoparticles (AgNPs) from the Bacillus brevis (NCIM 2533) was investigated. The synthesized AgNPs were characterized by various spectroscopic and microscopic techniques and confirmed the AgNPs having the surface Plasmon resonance peak at 420 nm and in the size range of 41–68 nm with spherical in shape by AFM and SEM analysis. It was confirmed and ascertained the presence of bioactive compounds in the AgNPs using TLC and FTIR. The In-vitro antibacterial activity of AgNPs showaed potential antibacterial property against multi-drug resistant pathogens such as Salmonella typhi and Staphylococcus aureus. The biosynthesized AgNPs could be utilized as antimicrobial agents for effective disease management.
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•Extracellular synthesis of Ag-BNPs from the Bacillus brevis (NCIM 2533).•Ag-BNPs were characterized by UV-Spec, FTIR, TLC, AFM & SEM.•Ag-BNPs showed antibacterial potency against S. typhi and S. aureus.