The Key Role of Nutritional Intervention in Delaying Disease Progression and the Therapeutic Management of Diabetic Kidney Disease-A Challenge for Physicians and Patients

• Published in: Journal of personalized medicine Vol. 14; no. 8; p. 778
• Main Authors: Peride, Ileana, Anastasiu, Miruna, Serban, Silvia Alexandra, Tiglis, Mirela, Ene, Razvan, Nechita, Ana-Maria, Neagu, Tiberiu Paul, Checherita, Ionel Alexandru, Niculae, Andrei
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23-07-2024; MDPI
• Subjects: Acidosis; Amino acids; Chronic kidney failure; Development and progression; Diabetes; Diabetes mellitus; Diabetic nephropathies; Diabetic nephropathy; Diet; Disease management; Drug therapy; Glucose; Health aspects; Hyperglycemia; Hypoglycemia; Kidney diseases; Malnutrition; Metabolism; Microvasculature; Mortality; Nephropathy; Nutrition; Nutritional status; Pathology; Physicians; Prevention; Proteins; Quality of life; Review; Structure-function relationships; Type 2 diabetes; Romania; diabetic kidney disease; chronic kidney disease; nutrition regimen; outcome
• ISSN: 2075-4426; 2075-4426
• DOI: 10.3390/jpm14080778

Chronic kidney disease (CKD) represents an increasingly common pathology that affects patients' quality of life, and it is frequently associated with a high mortality rate, especially in the final stages of the disease. At the same time, diabetes mellitus is a chronic disease that contributes to the increased number of patients with CKD through diabetic kidney disease (DKD). The alternation of hypoglycemia with hyperglycemia is a condition in the occurrence of microvascular complications of diabetes, including DKD, which involves structural and functional changes in the kidneys. The therapeutic management of diabetic nephropathy is a much-discussed topic, both from nutritional medical recommendations and a pharmacotherapy perspective. The diet starting point for patients with DKD is represented by a personalized and correct adjustment of macro- and micronutrients. The importance of nutritional status in DKD patients is given by the fact that it represents a modifiable factor, which contributes to the evolution and prognosis of the disease. Since, in most cases, it is necessary to restrict many types of food, malnutrition must be considered and avoided as much as possible.