Detection of T-Cadherin Expression in Mouse Embryos

The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the develo...

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Bibliographic Details
Published in:	Actanaturae Vol. 7; no. 2; pp. 87 - 94
Main Authors:	Rubina, K A, Smutova, V A, Semenova, M L, Poliakov, A A, Gerety, S, Wilkinson, D, Surkova, E I, Semina, E V, Sysoeva, V Yu, Tkachuk, V A
Format:	Journal Article
Language:	English
Published:	Russia (Federation) 01-04-2015
Subjects:	T-cadherin embryogenesis angiogenesis in situ hybridization
Online Access:	Get full text
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Summary:	The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2075-8251
DOI:	10.32607/20758251-2015-7-2-87-94