Radiophosphate imaging and bone densitometry in renal osteodystrophy

The histologic features of renal osteodystrophy vary from dialysis osteomalacia to osteitis fibrosa cystica. Commensurate with this, the number of osteoblasts and osteoclasts changes with the stage of the disease; the osteoblasts are virtually absent in dialysis osteomalacia and are numerous in oste...

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Bibliographic Details
Published in:	Current opinion in nephrology and hypertension Vol. 2; no. 6; p. 956
Main Author:	Rosenthall, L
Format:	Journal Article
Language:	English
Published:	England 01-11-1993
Subjects:	Bone Density - physiology Chronic Kidney Disease-Mineral and Bone Disorder - diagnostic imaging Chronic Kidney Disease-Mineral and Bone Disorder - physiopathology Densitometry Humans Parathyroid Glands - physiology Parathyroidectomy Radionuclide Imaging Technetium Tc 99m Medronate
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Summary:	The histologic features of renal osteodystrophy vary from dialysis osteomalacia to osteitis fibrosa cystica. Commensurate with this, the number of osteoblasts and osteoclasts changes with the stage of the disease; the osteoblasts are virtually absent in dialysis osteomalacia and are numerous in osteitis fibrosa. Radiophosphate accretion in bone increases with increasing osteoblastic activity, and the bone mineral status is determined by the net difference in osteoblastic and osteoclastic activity. The application of radionuclide imaging and dual radiographic absorptiometry mineral measurements in patients with renal osteodystrophy, renal transplants, and following parathyroidectomy for secondary hyperparathyroidism is reviewed.
ISSN:	1062-4821
DOI:	10.1097/00041552-199311000-00016