Intraocular extramedullary plasmacytoma in a cat

An 8‐year‐old, castrated male Domestic Short‐haired cat was referred for evaluation of a possible intraocular neoplasm following previous ocular trauma. The eye was blind, and uveitis and an iridal mass were noted on examination. An enucleation was performed and the mandibular lymph node excised. Hi...

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Bibliographic Details
Published in:	Veterinary ophthalmology Vol. 6; no. 2; pp. 177 - 181
Main Authors:	Michau, Tammy Miller, Proulx, David R., Rushton, Steven D., Olivry, Thierry, Dunston, Stanley M., Gilger, Brian C., Davidson, Michael G.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Science Ltd 01-06-2003
Subjects:	Animals Antineoplastic Agents - therapeutic use Blindness - etiology Blindness - veterinary Cat Diseases - diagnosis Cat Diseases - drug therapy Cat Diseases - pathology Cats Drug Therapy, Combination extramedullary Eye Injuries - complications Eye Injuries - veterinary Eye Neoplasms - complications Eye Neoplasms - diagnosis Eye Neoplasms - veterinary feline iris Lymphatic Metastasis Male Melphalan - therapeutic use neoplasia Orbit Evisceration - veterinary plasmacytoma Plasmacytoma - complications Plasmacytoma - diagnosis Plasmacytoma - veterinary Prednisone - therapeutic use
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Summary:	An 8‐year‐old, castrated male Domestic Short‐haired cat was referred for evaluation of a possible intraocular neoplasm following previous ocular trauma. The eye was blind, and uveitis and an iridal mass were noted on examination. An enucleation was performed and the mandibular lymph node excised. Histopathologic examination revealed neoplastic proliferation of plasma cells in the iris and lymph node. No other evidence of disseminated disease was detected. This is the first case reported of an intraocular extramedullary plasmacytoma in the cat. The variation in clinical manifestations and potential association with multiple myeloma are not known at this time. Disseminated metastasis from a primary plasmacytoma of the uveal tract could also involve the bone marrow and be indistinguishable from multiple myeloma. Early enucleation, as in trauma‐associated sarcomas, may be indicated to prevent metastasis. Periodic systemic evaluation for evidence of multiple myeloma should be performed.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1463-5216 1463-5224
DOI:	10.1046/j.1463-5224.2003.00277.x