9,10-seco-9,19-cyclolanostane triterpene from Salix caprea L. (Goat Willow)

Chemical investigation of low polar solvent extract of Salix caprea through chromatographic techniques led to the isolation of new triterpene as 1α,3β,25-trihydroxy-9(11)-ene-16-one-9,10-seco-9,19-cyclolanostane (1) along with fatty alcohols. The structure of compound 1 was established by IR, HRESI/...

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Bibliographic Details
Published in:	Natural product research Vol. 27; no. 2; pp. 171 - 175
Main Authors:	Tantry, Mudasir A., Shah, Saba, Dar, Mohammad Y., Mir, Mohammad M., Ghazanfar, Khalid, Sheikh, Faheem A., Khuroo, Mohammad A., Akbar, Seema
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis Group 01-01-2013
Subjects:	1α,3β,25-trihydroxy-9-ene-16-one-9,10-seco-9,19-cyclolanostane antiplasmodial activity Chloroform Chromatography Flowers - chemistry Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Molecular Structure Plant Extracts - analysis Plant Extracts - isolation & purification Plant Extracts - pharmacology Plasmodium falciparum - drug effects Salix - chemistry Salix caprea Triterpenes - analysis Triterpenes - isolation & purification Triterpenes - pharmacology
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Summary:	Chemical investigation of low polar solvent extract of Salix caprea through chromatographic techniques led to the isolation of new triterpene as 1α,3β,25-trihydroxy-9(11)-ene-16-one-9,10-seco-9,19-cyclolanostane (1) along with fatty alcohols. The structure of compound 1 was established by IR, HRESI/MS and NMR including 1D and 2D experiments. The compound 1 showed moderate in vitro antiplasmodial activity.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1478-6419 1478-6427
DOI:	10.1080/14786419.2012.665912