Electrochemically directed biofunctionalization of a lossy-mode resonance optical fiber sensor
In this work, we present a direct electrochemical biofunctionalization of an indium-tin-oxide-coated lossy-mode resonance optical fiber sensor. The functionalization using a biotin derivative was performed by cyclic voltammetry in a 10 mM biotin hydrazide solution. All stages of the experiment were...
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| Published in: | Optics express Vol. 28; no. 11; pp. 15934 - 15942 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
25-05-2020
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| Online Access: | Get full text |
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| Summary: | In this work, we present a direct electrochemical biofunctionalization of an indium-tin-oxide-coated lossy-mode resonance optical fiber sensor. The functionalization using a biotin derivative was performed by cyclic voltammetry in a 10 mM biotin hydrazide solution. All stages of the experiment were simultaneously verified with optical and electrochemical techniques. Performed measurements indicate the presence of a poly-biotin layer on the sensor’s surface. Furthermore, dual-domain detection of 0.01 and 0.1 mg/mL of avidin confirms the sensor’s viability for label-free detection. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1094-4087 1094-4087 |
| DOI: | 10.1364/OE.390780 |