Diffuse alveolar hemorrhage due to ketorolac tromethamine

Drug-induced lung disease (DILD) is a common but frequently missed diagnosis. Therefore, a high index of clinical suspicion and familiarity with the clinical syndromes associated with DILD are important in making the diagnosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the mostly comm...

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Bibliographic Details
Published in:	Pharmacology Vol. 92; no. 1-2; p. 11
Main Authors:	Marak, Creticus P, Alappan, Narendrakumar, Shim, Chang, Guddati, Achuta K
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-2013
Subjects:	Adult Anti-Inflammatory Agents, Non-Steroidal - adverse effects Hemorrhage - chemically induced Hemorrhage - diagnostic imaging Humans Ketorolac Tromethamine - adverse effects Lung Diseases - chemically induced Lung Diseases - diagnostic imaging Male Pulmonary Alveoli Tomography, X-Ray Computed
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Summary:	Drug-induced lung disease (DILD) is a common but frequently missed diagnosis. Therefore, a high index of clinical suspicion and familiarity with the clinical syndromes associated with DILD are important in making the diagnosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the mostly commonly used classes of medications. NSAIDs are safe when used at prescribed doses. Side effects from use of NSAIDs are not uncommon and can affect almost every organ system in the body. NSAIDs are notorious for causing pulmonary toxicity, the common ones being bronchospasm and hypersensitivity reactions. Diffuse alveolar hemorrhage (DAH) secondary to NSAIDs is uncommon. Here, we report a case of DAH secondary to the use of ketorolac tromethamine.
ISSN:	1423-0313
DOI:	10.1159/000351844