The therapeutic journey of pyridazinone

Pyridazinones have drawn a substantial attention within the field of research analysis and development. The moiety is a subject matter of intensive research because of its wide spectrum of biological activities and therapeutic applications. The synthesis of pyridazinone and investigation of their ch...

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Bibliographic Details
Published in:	European journal of medicinal chemistry Vol. 123; pp. 256 - 281
Main Authors:	Akhtar, Wasim, Shaquiquzzaman, M., Akhter, Mymoona, Verma, Garima, Khan, Mohemmed Faraz, Alam, M. Mumtaz
Format:	Journal Article
Language:	English
Published:	France Elsevier Masson SAS 10-11-2016
Subjects:	Animals Anti-inflammatory and analgesic Anticancer Antiviral Biological activity Heterocyclic Humans Pyridazines - pharmacology Pyridazines - therapeutic use Pyridazinone Antiviral Pyridazinone Anti-inflammatory and analgesic Anticancer Heterocyclic Biological activity
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Summary:	Pyridazinones have drawn a substantial attention within the field of research analysis and development. The moiety is a subject matter of intensive research because of its wide spectrum of biological activities and therapeutic applications. The synthesis of pyridazinone and investigation of their chemical and biological activities have gained additional importance in recent years. In this review, we have compiled and discussed various biological and therapeutic potential of pyridazinone derivatives. [Display omitted] •Pyridazinone: Six membered heterocyclic ring with diverse pharmacological activities.•Provides an overview of one based work going on in the field of development of pyridazinone based pharmacological agents.•Useful for researchers planning to work on.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0223-5234 1768-3254
DOI:	10.1016/j.ejmech.2016.07.061