Incidental Detection of Clinically Occult Pituitary Adenoma on Whole-Body FDG PET Imaging

A patient with metastatic leiomyosarcoma demonstrated a focus of intense hypermetabolism in the sellar region in a posttreatment F-18 FDG PET. Further workup with magnetic resonance imaging revealed a pituitary adenoma. Endocrinologic evaluation was consistent with acromegaly. The patient underwent...

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Bibliographic Details
Published in:	Clinical nuclear medicine Vol. 31; no. 1; pp. 42 - 43
Main Authors:	Koo, Chi Wan, Bhargava, Peeyush, Rajagopalan, Vandana, Ghesani, Munir, Sims-Childs, Hajar, Kagetsu, Nolan J
Format:	Journal Article
Language:	English
Published:	United States Lippincott Williams & Wilkins, Inc 01-01-2006
Subjects:	Adenoma - diagnostic imaging Aged Fluorodeoxyglucose F18 Humans Incidental Findings Male Neoplasms, Unknown Primary - diagnostic imaging Pituitary Neoplasms - diagnostic imaging Pituitary Neoplasms - secondary Positron-Emission Tomography Radiopharmaceuticals Whole Body Imaging
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Summary:	A patient with metastatic leiomyosarcoma demonstrated a focus of intense hypermetabolism in the sellar region in a posttreatment F-18 FDG PET. Further workup with magnetic resonance imaging revealed a pituitary adenoma. Endocrinologic evaluation was consistent with acromegaly. The patient underwent transsphenoidal hypophysectomy with pathology consistent with a growth hormone-secreting pituitary macroadenoma. This case demonstrates early detection of a pituitary adenoma by whole-body FDG PET and emphasizes the importance of pursuing incidental findings detected in the sella on PET imaging.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0363-9762 1536-0229
DOI:	10.1097/01.rlu.0000191779.75532.05