Effect of hematocrit on blood dynamics on a compact disc platform

We investigate blood flow dynamics on a rotationally actuated lab-on-a-compact disk (LOCD) platform, as a function of the hematocrit level of the blood sample. In particular, we emphasize the resultant implications on the critical fluidic parameters, such as on burst frequency and volumetric flow ra...

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Bibliographic Details
Published in:	Analyst (London) Vol. 140; no. 5; p. 1432
Main Authors:	Kar, Shantimoy, Dash, Monika, Maiti, Tapas Kumar, Chakraborty, Suman
Format:	Journal Article
Language:	English
Published:	England 07-03-2015
Subjects:	Compact Disks Hematocrit Hemodynamics Humans Microfluidic Analytical Techniques - instrumentation Microfluidic Analytical Techniques - methods Models, Theoretical Rheology
Online Access:	Get more information
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Summary:	We investigate blood flow dynamics on a rotationally actuated lab-on-a-compact disk (LOCD) platform, as a function of the hematocrit level of the blood sample. In particular, we emphasize the resultant implications on the critical fluidic parameters, such as on burst frequency and volumetric flow rate. Our results can be utilized as a characteristic guideline to predict the hematological parameters of a given small amount of blood sample from the observed flow characteristics, and can give rise to a new paradigm of medical diagnostics driven by interactions between blood rheology and rotational forces on an inexpensive platform, with minimal sample consumption.
ISSN:	1364-5528
DOI:	10.1039/c4an02020k