Red cell transfusion therapy in chronic anemia

This article discusses anemia, the evaluation of symptoms, and the compensatory mechanisms that are brought into play by chronic anemia. The oxygen dissociation curve is described as is the effect of 2,3-DPG on hemoglobin-oxygen binding. Human tolerance to anemia is discussed and the article conclud...

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Bibliographic Details
Published in:	Hematology/oncology clinics of North America Vol. 8; no. 6; p. 1045
Main Author:	Rossi, E C
Format:	Journal Article
Language:	English
Published:	United States 01-12-1994
Subjects:	2,3-Diphosphoglycerate Anemia - blood Anemia - therapy Chronic Disease Diphosphoglyceric Acids - blood Erythrocyte Transfusion Humans
Online Access:	Get more information
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Summary:	This article discusses anemia, the evaluation of symptoms, and the compensatory mechanisms that are brought into play by chronic anemia. The oxygen dissociation curve is described as is the effect of 2,3-DPG on hemoglobin-oxygen binding. Human tolerance to anemia is discussed and the article concludes with proposed transfusion strategies in chronic anemia.
ISSN:	0889-8588
DOI:	10.1016/S0889-8588(18)30121-7