Rapid prototyping for quantifying belief weights of competing hypotheses about emergent diseases

• Published in: Journal of environmental management Vol. 337; p. 117668
• Main Authors: Robertson, Ellen P., Walsh, Daniel P., Martin, Julien, Work, Thierry M., Kellogg, Christina A., Evans, James S., Barker, Victoria, Hawthorn, Aine, Aeby, Greta, Paul, Valerie J., Walker, Brian K., Kiryu, Yasunari, Woodley, Cheryl M., Meyer, Julie L., Rosales, Stephanie M., Studivan, Michael, Moore, Jennifer F., Brandt, Marilyn E., Bruckner, Andrew
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-07-2023
• Subjects: Animals; Anthozoa; Bayes Theorem; Coral reefs; Disease ecology; Etiology; Hypothesis testing; Stony coral tissue loss disease; Uncertainty; Wildlife disease; Coral reefs; Hypothesis testing; Wildlife disease; Disease ecology; Etiology; Stony coral tissue loss disease
• ISSN: 0301-4797; 1095-8630
• DOI: 10.1016/j.jenvman.2023.117668

Emerging diseases can have devastating consequences for wildlife and require a rapid response. A critical first step towards developing appropriate management is identifying the etiology of the disease, which can be difficult to determine, particularly early in emergence. Gathering and synthesizing existing information about potential disease causes, by leveraging expert knowledge or relevant existing studies, provides a principled approach to quickly inform decision-making and management efforts. Additionally, updating the current state of knowledge as more information becomes available over time can reduce scientific uncertainty and lead to substantial improvement in the decision-making process and the application of management actions that incorporate and adapt to newly acquired scientific understanding. Here we present a rapid prototyping method for quantifying belief weights for competing hypotheses about the etiology of disease using a combination of formal expert elicitation and Bayesian hierarchical modeling. We illustrate the application of this approach for investigating the etiology of stony coral tissue loss disease (SCTLD) and discuss the opportunities and challenges of this approach for addressing emergent diseases. Lastly, we detail how our work may apply to other pressing management or conservation problems that require quick responses. We found the rapid prototyping methods to be an efficient and rapid means to narrow down the number of potential hypotheses, synthesize current understanding, and help prioritize future studies and experiments. This approach is rapid by providing a snapshot assessment of the current state of knowledge. It can also be updated periodically (e.g., annually) to assess changes in belief weights over time as scientific understanding increases. Synthesis and applications: The rapid prototyping approaches demonstrated here can be used to combine knowledge from multiple experts and/or studies to help with fast decision-making needed for urgent conservation issues including emerging diseases and other management problems that require rapid responses. These approaches can also be used to adjust belief weights over time as studies and expert knowledge accumulate and can be a helpful tool for adapting management decisions.
•We developed methods for rapidly assessing hypotheses about disease etiology.•Methods included formal expert elicitation and Bayesian hierarchical modeling.•We illustrate this approach for a recently emerged disease in coral reefs.•These methods are useful for fast decision-making for conservation issues.•These methods can help adapt management decisions over time as knowledge accumulates.