Successful Treatment of Hepatocellular Carcinoma Complicated by Fanconi Anemia

• Published in: Case reports in gastroenterology Vol. 11; no. 1; pp. 29 - 35
• Main Authors: Takahashi, Koji, Suzuki, Eiichiro, Yokoyama, Masayuki , Inoue, Masanori, Wakamatsu, Toru, Saito, Tomoko, Kusakabe, Yuko, Ogasawara, Sadahisa, Ooka, Yoshihiko, Tawada, Akinobu, Nagao, Yuhei, Nakaseko, Chiaki, Chiba, Tetsuhiro
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 27-01-2017; Karger Publishers
• Subjects: Anemia; Antibiotics; Biopsy; Blood; Bone marrow; Case reports; Deoxyribonucleic acid; DNA; Fanconi anemia; Genes; Genomics; Hematology; Hepatitis; Hepatocellular carcinoma; Hepatology; Laryngeal cancer; Leukemia; Liver cancer; Mutation; Patients; Single Case; Transcatheter arterial embolization; Transplants & implants; Tumors; Japan; Fanconi anemia; Transcatheter arterial embolization; Hepatocellular carcinoma
• ISSN: 1662-0631; 1662-0631
• DOI: 10.1159/000454710

A 42-year-old woman with liver tumors was referred to our hospital. Her condition was complicated by Fanconi anemia, and she had undergone total laryngectomy 8 years ago. On admission, contrast-enhanced computed tomography revealed hypervascular tumors in the right hepatic lobe. Ultrasound-guided tumor biopsy revealed that the tumor comprised moderately differentiated hepatocellular carcinoma. Although the patient exhibited preserved liver function (Child-Pugh A), complete blood count revealed severe pancytopenia. Eventually, the tumor was successfully treated by transcatheter arterial embolization (TAE). Both platelet transfusion and systemic administration of antibiotics were performed. She was discharged 35 days after TAE.