N-octanoylated ghrelin peptide inhibits bovine oocyte meiotic resumption

•50 ng/mL ghrelin could inhibit bovine oocytes germinal vesicle breakdown.•Increased cAMP and cGMP levels in CCs and DOs contributed to this inhibition.•Inhibitory ghrelin benefits the developmental competence of matured oocytes.•Ghrelin could act as a pharmaceutical meiosis inhibitor for bovine ooc...

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Bibliographic Details

Published in:	General and comparative endocrinology Vol. 263; pp. 7 - 11
Main Authors:	Xu, X.L., Bai, J.H., Feng, T., Xiao, L.L., Song, Y.Q., Xiao, Y.X., Liu, Y.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-07-2018
Subjects:	Bovine Germinal vesicle breakdown Meiotic resumption N-octanoylated ghrelin Oocyte maturation Bovine Meiotic resumption Germinal vesicle breakdown N-octanoylated ghrelin Oocyte maturation
Online Access:	Get full text
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