Serum factor in cystic fibrosis: correlation with clinical parameters

Serum factor in cystic fibrosis: correlation with clinical parameters

The relationship between the activity of the cystic fibrosis serum ciliary dyskinesia factor, detected by the rabbit tracheal bioassay, and clinical status of the patient has been investigated in children, 1-24 years old, with cystic fibrosis. No significant correlation was found between the amount...

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Bibliographic Details
Published in:Pediatric research Vol. 13; no. 6; pp. 729 - 732
Main Authors: Nagy, E C, Khan, S, Sturgess, J M
Format: Journal Article
Language:English
Published: United States 01-06-1979
Subjects:
Adolescent
Adult
Animals
Biological Assay
Carbon Dioxide - blood
Child
Child, Preschool
Cystic Fibrosis - blood
Cystic Fibrosis - enzymology
Female
Galactosyltransferases - blood
Humans
Infant
Male
Oxygen - blood
Peptides - blood
Rabbits
Respiratory Function Tests
Trachea
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Summary:The relationship between the activity of the cystic fibrosis serum ciliary dyskinesia factor, detected by the rabbit tracheal bioassay, and clinical status of the patient has been investigated in children, 1-24 years old, with cystic fibrosis. No significant correlation was found between the amount of serum factor activity and age, clinical status assessed by the Schwachman score, pulmonary function (vital capacity, functional residual capacity, total lung capacity, residual volume, maximum breathing capacity, maximal midinspiratory flow, and maximal midexpiratory flow) or blood gas levels (pCO2, pO2). The activity showed no significant relationship to serum galactosyltransferase activity in children with cystic fibrosis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0031-3998
1530-0447
DOI:10.1203/00006450-197906000-00001