On drug artifacts in middle molecule analysis

On drug artifacts in middle molecule analysis

In a retrospective study of 58 nondialyzed uremic patients, artifacts originating from furosemide, methyldopa, hydralazine, allopurinol and beta-blocking agents on determination of plasma middle molecules could not be substantiated. Furosemide administration did not have any influence on middle mole...

Full description

Saved in:
Bibliographic Details
Published in:Nephron (2015) Vol. 39; no. 2; p. 73
Main Authors: Asaba, H, Zimmerman, L, Bergström, J
Format: Journal Article
Language:English
Published: Switzerland 01-01-1985
Subjects:
Furosemide - pharmacology
Humans
Salicylates - pharmacology
Salicylic Acid
Toxins, Biological - analysis
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In a retrospective study of 58 nondialyzed uremic patients, artifacts originating from furosemide, methyldopa, hydralazine, allopurinol and beta-blocking agents on determination of plasma middle molecules could not be substantiated. Furosemide administration did not have any influence on middle molecule determination in hemodialysis patients. The salicyclic acid administration in normal subjects resulted in increased urinary excretion of fraction 7c; the role of salicylic acid needs to be further investigated.
ISSN:1660-8151
DOI:10.1159/000183347