Impact of Morbid Obesity on the Outcomes of Type II Endometrial Cancer: a Cohort Study

• Published in: Indian journal of surgical oncology Vol. 13; no. 3; pp. 453 - 458
• Main Authors: Gaballa, Khaled, Metwally, Islam H., Refky, Basel, Awny, Shadi, Abdelkhalek, Mohamed, Hamdy, Mohamed
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01-09-2022; Springer Nature B.V
• Subjects: Cancer surgery; Cohort analysis; Medicine; Medicine & Public Health; Oncology; Original; Original Article; Surgery; Surgical Oncology; Endometrial cancer; Obesity Non-endometrioid carcinoma; Hysterectomy
• ISSN: 0975-7651; 0976-6952
• DOI: 10.1007/s13193-022-01503-z

Obesity has long been associated with endometrial cancer. However, there is a paucity of studies addressing the impact of morbid obesity in type II endometrial cancer on oncologic and surgical outcomes. In this study, the author retrospectively compared morbid to non-morbid obese in clinico-epidemiologic, surgical, and oncologic outcomes. Both groups were comparable as regards all clinico-epidemiologic parameters. Vaginal involvement, survival, and recurrence were also comparable between the 2 groups. Para-aortic adenopathy and treatment with preoperative therapy were the only significant predictors of DFS. Surgery is feasible with equivalent complications and oncologic outcomes in morbidly obese patients with type II endometrial cancer.