Emollients and photo(chemo)therapy: a call for caution

• Published in: Dermatology (Basel) Vol. 192; no. 3; p. 242
• Main Authors: Gabard, B, Treffel, P, Bieli, E, Schwab, S
• Format: Journal Article
• Language: English
• Published: Switzerland 01-01-1996
• Subjects: Contraindications; Emollients - pharmacology; Emollients - therapeutic use; In Vitro Techniques; Models, Theoretical; Photochemotherapy; Phototherapy; Ultraviolet Rays
• ISSN: 1018-8665
• DOI: 10.1159/000246375

Emollients used for skin care, treatment of a disease or lubrication, before irradiation during the course of phototherapy or photochemotherapy, may significantly interfere with the transmission of UV light and may influence the outcome of the therapy.
These experiments should characterize and quantify the possible interactions of usual emollients with UV light transmission.
The method was an in vitro technique similar to the one already used for the determination of sun protection factors of topical sunscreen preparations.
Among the products tested, two showed a significant photoprotection capable of interfering with the course of therapy. Oils enhanced UV light transmission significantly.
Emollients may show significant interference with UV light transmission during phototherapy or photochemotherapy. The outcome and course of the therapy could thus be significantly modified.