The effect of age, gender, and sexual maturation on the caffeine breath test

This study demonstrated the feasibility of utilizing the (3-13C-methyl) caffeine breath test (CBT) in children and adolescents, and examined the effect of gender, age, and puberty on the CBT. The CBT, expressed as the 2-hour accumulative exhalation of labeled CO2 (2-hour CO2), was compared to the CB...

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Bibliographic Details
Published in:	Developmental pharmacology and therapeutics Vol. 9; no. 6; p. 375
Main Authors:	Lambert, G H, Schoeller, D A, Kotake, A N, Flores, C, Hay, D
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-1986
Subjects:	Adolescent Adult Age Factors Aging Breath Tests - methods Caffeine - metabolism Carbon Dioxide - metabolism Child Child, Preschool Cytochrome P-450 Enzyme System - metabolism Female Humans Male Sex Factors Sexual Maturation
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Summary:	This study demonstrated the feasibility of utilizing the (3-13C-methyl) caffeine breath test (CBT) in children and adolescents, and examined the effect of gender, age, and puberty on the CBT. The CBT, expressed as the 2-hour accumulative exhalation of labeled CO2 (2-hour CO2), was compared to the CBT results in the adult. The 2-hour CO2 values were higher in the children than the adult, and the decrease in the CO2 values occurred in males during late puberty and in females during early puberty.
ISSN:	0379-8305
DOI:	10.1159/000457262